Author: Patrick Murray
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Month 29
April 14, 2026 WoW. The new technologies seem to be stepping up more rapidly than effort. Now it’s a bi-specific genetically engineer material designed to capture a T-cell in a human’s body on one side, and on the other side, has something to capture a PCa cell, essentially dragging the T-cell over to the selected…
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Avoiding, Treating & Curing Cancer With the Immune System
Thank you to one commenter for introducing me to this totally awesome interview of Dr. Alex Marson, conducted by Dr. Andrew Huberman. It’s a two and a half hour video interview where they discuss a wide range of aspects associated with the genetic engineering revolution occurring today in all subfields of biology. They speak of…
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CAR T-cell therapy works differently than mRNA-vaccine therapy for PCa
CAR T-cell reprogramming and mRNA vaccines are both immunotherapies for prostate cancer (PCa), but they differ fundamentally in their mechanism of action, manufacturing, and approach to immune activation. CAR T-cell therapy is a “living drug” approach involving complex ex vivo engineering of a patient’s own immune cells to directly attack tumor cells, whereas mRNA vaccines are an “educational” approach that teaches the…
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CAR T-cell reprogramming represents a critical strategy for treating PCa
CAR T-cell reprogramming is a critical strategy for treating prostate cancer because it addresses the major biological barriers that have historically made this “immunologically cold” tumor resistant to standard CAR T therapies. While CAR T-cell therapy has excelled in blood cancers (yet another recent publication, the full version here), its success in prostate cancer depends…
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Genetic Approaches Begin to Revolutionize PCa therapies.
At this time, genetic approaches to fight PCa breaks down to two techniques, the DNA approach, and the mRNA approach. The DNA approach uses CRISPR technology Clustered Regularly Interspaced Short Palindromic Repeats (CRIPSR) technology leads the way in the DNA approach to fighting PCa. Cancer results from unfavorable DNA alterations that creates cancer cells from…
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mRNA therapy represents a revolution in PCa treatment
I have known for a while that the same mRNA techniques used to create COVID 2 vaccines have moved on to create cancer therapies. Some are very successful, very expensive, but restricted to cancers outside the realm of PCa. And I have been wondering for a while what was happening in the world of mRNA…
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Month 27 and 28
March 23, 2026 Reducing Insulin Growth Factor 1 (IGH1) in the diet slows and can reverse PCa progression. I have been aware of this since my daughter bought me the book, How Not to Die: Discover the Foods Scientifically Proven to Prevent and Reverse Disease, by Michael Greger, M.D. There is a chapter on specific…
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Month 26
January 24, 2026 Well, it’s been a while since posting. I have been traveling extensively, enjoying an awesome Holiday Cruise offered by the Italian Cruise line, MSC. After hearing mixed reviews for MSC, we came away with a very favorable impression. The standard rooms were generously sized, and the upgrade to an unobstructed balcony was…
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Month 25
Best of Science to Everyone ! December 20, 2025 Merry Christmas or other Holiday over the Winter Break. I teach part time and look forward to the week off. I did get a capsule making machine, but I am undecided whether it will be Apigenin or Luteolin as a hand-made supplement. The best to everyone.…
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Apigenin Strategy
I didn’t realize until recently how important Apigenin turns out to be in my fight against PCa. As my research broadened, Genistein also came into the picture as a significant fighter of PCa. The anticancer efficacies of these two flavones can be confirmed by in-vitro and in-vivo studies. (1) Here is another key research paper that shows that “Apigenin…
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Month 24
November 26, 2025 Another blogger suggests Luteolin is the better researched and more promising anti PCa micronutrient as compared to Apigenin. And I am already taking large amounts of Punicic Acid through pomegranate seed oil. How do I properly step up either Luteolin or Apigenin to demonstrated levels of PCa cellular kills ? And how…
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Month 22
October 31, 2025 Hi Everyone. Just wanted to report out that my liver enzymes have been normal throughout my 2 years of AS/Veganism/Supplements. In case you haven’t been following the conversation, I got an email from another ASer about his liver enzymes being moderately out of the normal range. I just happened to have my…
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Month 21
September 14, 2025 Hi Everyone. I’m back from my probably once-in-a-lifetime travel summer. It was exhausting as much as it was fun, and I have started my new year at high school math, where I teach part time. May they exhaustion continue? One poster passed along an interesting question that has lead to some new…
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Month 20
August 29, 2025 Closing in on the end of the month and checking out of yet another hotel in London, its a busy and exciting time with my daughter’s wedding on the 30th. I am trying to commit myself to posting something every day for another week or so to the new Reddit PCa AS…
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Here’s How I Am Doing It !
Life is good for me, 20 months into Active Surveillance. I continue to be asymptomatic. My stream has returned to normal and my prostate is 12% smaller, without Finasteride. My PSA was over 6, now it’s 3. My 1.4 cm lesion PIRADS 4 on MRI 1 vanished on MRI 2 a year later, at the…
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Months 17, 18, and 19
July 4, 2005 Well, it’s been a while and I have some new news. I have been focusing on PSO, luteolin, and elegiac acid, with a smattering of other supplements. I have taken out the Rosemary / Ursolic Acid. I have two types of PSO, and I chose one to go with. Another AS-oriented individual…
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Months 15 and 16
April 29, 2025 Who would think after a long break not posting anything, then the day after the April 28th post, I get a reply to a 5 month old social media post where the poster talks about his Dad who was diagnosed at 63 with PCa who did something similar to what I am…
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Month 14
February 21, 2025 Well, Good news and bad news. While the new lesion was benign, and there is no signs of metastatic activity, although microscopically anything could be happening. Unfortunately, four random cores in the vicinity of the original tumor were 3/4. Three of those were 10% Grade 4 and one was 20% Grade 4.…
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Month 13
January 25, 2025 update Well, for one, it’s my twin daughters birthday. They helped me get this site going and encouraged me along the way. My second biopsy is February 7. It’s not necessary like the first one since my tumor is low suspect for PC, but since I am already on AS, I will…
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The Existential Life of an AS Guy
“What do we mean by that?” , “Yeah, what do we mean by that?” Exact quotes or not, Soupy Sales and Fang come to mind. Is it OK for an Active Surveillance (AS) Guy comment in non-AS forums? A fair number of folks have questioned whether an AS guy should be posting in advanced prostate…